Overview of Selected Chemical Compounds and Intermediates

Overview of Selected Chemical Compounds and Intermediates

Blog Article

one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This can be an impurity relevant to bortezomib, a proteasome inhibitor Employed in the treatment of multiple myeloma. Its synthesis or research is vital for ensuring the purity and basic safety in the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor during the synthesis of abiraterone acetate, a drug Utilized in the remedy of prostate cancer by inhibiting androgen generation.
Imatinib Intermediate (CAS NO. 152460-10-one): A important compound during the synthesis of imatinib, a drug that targets precise sorts of cancer, together with Continual myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Employed in the synthesis of docetaxel, a chemotherapy medication that treats numerous cancers which include breast, lung, and prostate cancer.
two. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): These are intermediates from the synthesis of gemcitabine, an anti-cancer drug. Their examine is vital for optimizing the production course of hydrochloride action and ensuring significant purity.
Lapatinib Intermediate (CAS NO. 231278-84-5): Lapatinib is applied to treat breast cancer, and these intermediates are linked to its production.
Fulvestrant Intermediates: Fulvestrant is undoubtedly an estrogen receptor antagonist Employed in the treatment method of breast most cancers. Numerous intermediates help in the synthesis of the drug.
Paclitaxel Side Chain Acid (CAS NO. 949023-sixteen-nine): This intermediate is Employed in the synthesis of paclitaxel, a chemotherapy drug efficient in dealing with cancers for example ovarian, breast, and lung most cancers.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug used in the treatment of colorectal cancer and tiny cell Pemetrexed Intermediate lung cancer.
3-Amino-1-hydroxyadamantane (CAS 702-82-9): This compound is involved with the synthesis of adamantane derivatives, that have different apps, together with antiviral properties.
Vildagliptin Intermediates: Used in the production of vildagliptin, an oral drug for variety two diabetic issues that inhibits the enzyme DPP-4 to manage blood sugar levels.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-one): This compound is linked to the synthesis of assorted gluconic acid derivatives, which are used in food, pharmaceutical, and industrial applications.
Canagliflozin Intermediate two: A precursor in the synthesis of canagliflozin, a medication used to manage style two diabetes by inhibiting sodium-glucose co-transporter 2 (SGLT2).